| Hydra | Runes | 15–45 | 1/14.2 | >99.99% | Konar 125–190 Mortimer 150–200 |
| Wyrm | Runes | 25–30 | 1/15.2 | 99.9% | Chaeldar 60–100 Konar 125–190 Nieve 80–145 Duradel 100–160 Mortimer 80–120 |
| Ankou Members' worlds | Runes and ammunition | 11 | 1/16.7 | 98.2% | Krystilia 75–125 Vannaka 25–35 Konar 50–50 Nieve 50–90 Duradel 50–80 |
| Abyssal demon Wilderness Slayer Cave | Runes | 7 | 1/17 | 99.99% | Krystilia 75–125 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 Mortimer 120–180 |
| Lava dragon | Runes and ammunition | 20 | 1/18.3 | 93.3% | Krystilia 35–60 |
| Black demon Wilderness Slayer Cave | Runes | 7 | 1/18.5 | 99.99% | Krystilia 100–150 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 |
| Shadow warrior | Runes | 2 | 1/21.3 | 99.2% | Vannaka 30–80 Chaeldar 70–130 |
| Whirlpool | Runes | 5 | 1/25 | 98.9% | Chaeldar 30–50 Konar 80–100 Nieve 100–120 Duradel 100–120 |
| Araxyte Level 96 | Runes | 15–18 | 1/25.4 | 99.8% | Nieve 40–60 Duradel 60–80 Mortimer 120–180 |
| Araxyte Level 146 | Runes | 30–36 | 1/25.4 | 99.8% | Nieve 40–60 Duradel 60–80 Mortimer 120–180 |
| Bloodveld | Runes | 10 | 1/25.6 | 99.7% | Krystilia 70–110 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 Mortimer 120–180 |
| Feral Vampyre | Runes | 1 | 1/25.6 | 99.8% | Mazchna 10–20 Vannaka 10–20 Chaeldar 80–100 Konar 100–160 Nieve 110–170 Duradel 100–210 |
| Frost dragon | Runes and ammunition | 10–20 | 1/26 | 97.6% | Nieve 60–100 Duradel 70–120 |
| Nechryael | Runes | 15–20 | 1/29 | 99.8% | Krystilia 75–125 Vannaka 40–90 Chaeldar 70–130 Konar 110–110 Nieve 110–170 Duradel 130–200 Mortimer 150–200 |
| Ankou Wilderness Slayer Cave | Runes and ammunition | 11 | 1/30.7 | 88.4% | Krystilia 75–125 Vannaka 25–35 Konar 50–50 Nieve 50–90 Duradel 50–80 |
| Spitting Wyvern | Runes and ammunition | 15 | 1/30.7 | 68.6% | Chaeldar 10–20 Konar 15–30 Nieve 5–25 Duradel 20–50 |
| Ice giant Wilderness Slayer Cave | Runes and ammunition | 5 | 1/31 | 83.5% | Krystilia 100–150 Vannaka 30–80 |
| Abyssal demon Standard and Catacombs of Kourend | Runes | 7 | 1/32 | 99.1% | Krystilia 75–125 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 Mortimer 120–180 |
| Black demon Level 172, 178, and 184 | Runes | 7 | 1/32 | 99.5% | Krystilia 100–150 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 |
| Dark beast | Runes | 15 | 1/32 | 79.6% | Konar 10–15 Nieve 10–20 Duradel 10–20 Mortimer 40–60 |
| Fire giant | Runes and ammunition | 5 | 1/32 | 99.5% | Krystilia 75–125 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 |
| Locust rider | Runes and ammunition | 18 | 1/32 | 76.0% | Nieve 30–60 |
| Red dragon | Runes and ammunition | 2 | 1/32 | 78.2% | Konar 30–50 Nieve 30–80 Duradel 30–65 |
| Skeletal Wyvern | Runes and ammunition | 25 | 1/32 | 61.4% | Chaeldar 10–20 Konar 5–12 Nieve 5–15 Duradel 20–40 |
| Ankou Members' worlds | Runes and ammunition | 5 | 1/33.3 | 86.2% | Krystilia 75–125 Vannaka 25–35 Konar 50–50 Nieve 50–90 Duradel 50–80 |
| Revenant demon | Other | 50–100 | 1/35 | 86.8% | Krystilia 40–100 |
| Lesser demon Wilderness Slayer Cave | Runes | 10 | 1/39 | 92.6% | Krystilia 80–120 Vannaka 40–90 Chaeldar 70–130 |
| Greater demon Wilderness Slayer Cave | Runes | 20 | 1/41 | 98.3% | Krystilia 100–150 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 |
| Black dragon | Runes and ammunition | 15 | 1/42.7 | 29.9% | Krystilia 8–16 Konar 10–15 Nieve 10–20 Duradel 10–20 |
| Black dragon Wilderness Slayer Cave | Runes and ammunition | 10 | 1/42.7 | 29.9% | Krystilia 8–16 Konar 10–15 Nieve 10–20 Duradel 10–20 |
| Bloodveld | Runes | 3 | 1/42.7 | 97.1% | Krystilia 70–110 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 Mortimer 120–180 |
| Bronze dragon | Runes and ammunition | 15 | 1/42.7 | 61.3% | Konar 30–40 Nieve 30–40 Duradel 35–45 |
| Waterfiend | Runes and ammunition | 17 | 1/42.7 | 98.0% | Konar 120–170 Duradel 130–200 |
| Ankou Wilderness Slayer Cave | Runes and ammunition | 8 | 1/46 | 76.0% | Krystilia 75–125 Vannaka 25–35 Konar 50–50 Nieve 50–90 Duradel 50–80 |
| Aviansie | Runes | 11 | 1/64 | 92.0% | Krystilia 75–125 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 120–200 |
| Brine rat | Runes | 4 | 1/64 | 91.0% | Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 |
| Infernal Mage | Catalytic runes | 4 | 1/64 | 49.2% | Vannaka 40–90 Mortimer 35–50 |
| Black demon Wilderness Slayer Cave | Runes | 5 | 1/74 | 89.4% | Krystilia 100–150 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 |
| Ankou Wilderness Slayer Cave | Runes and ammunition | 18 | 1/92 | 50.9% | Krystilia 75–125 Vannaka 25–35 Konar 50–50 Nieve 50–90 Duradel 50–80 |
| Bandit Level 22 | Runes | 2 | 1/128 | 54.4% | Krystilia 75–125 |
| Bloodveld | Runes | 30 | 1/128 | 69.2% | Krystilia 70–110 Vannaka 40–90 Chaeldar 70–130 Konar 120–170 Nieve 120–185 Duradel 130–200 Mortimer 120–180 |
| Earth warrior | Runes | 2 | 1/128 | 54.4% | Krystilia 75–125 |
| Feral Vampyre | Runes | 2 | 1/128 | 70.3% | Mazchna 10–20 Vannaka 10–20 Chaeldar 80–100 Konar 100–160 Nieve 110–170 Duradel 100–210 |
| Green dragon Wilderness Slayer Cave | Runes | 5 | 1/128 | 47.8% | Krystilia 65–100 |
| Ice giant | Runes and ammunition | 2 | 1/128 | 35.0% | Krystilia 100–150 Vannaka 30–80 |
| Ice warrior | Runes and ammunition | 2 | 1/128 | 39.9% | Krystilia 100–150 Mazchna 40–50 Vannaka 40–90 |
| Moss giant | Runes and ammunition | 1 | 1/128 | 39.9% | Krystilia 100–150 Vannaka 40–90 |
| Otherworldly being | Runes | 2 | 1/128 | 39.9% | Vannaka 40–90 |
| Bandit Level 130 drops (members only) | Runes | 6 | 1/143 | 50.4% | Krystilia 75–125 |
